![]() ![]() Besides its general anti‐inflammatory action, Given at doses up to 2 g/day, ginger is effective at controlling vomiting without side effects. The antiemetic action of ginger has been investigated in various conditions including motion sickness, pregnancy, post‐anesthesia, post‐surgery, and chemotherapy‐induced nausea and vomiting. The active phenolic compounds of ginger, that is, gingerols, zingiberene and shogaols, have also anti‐inflammatory and anti‐oxidant properties. Ginger ( Zingiber officinale) is a spice with a long history of use as traditional remedy for nausea and vomiting. The antiemetic drugs most frequently prescribed in Europe and Italy are domperidone, a dopamine receptor antagonist, and ondansetron, a 5‐HT 3 antagonist.Ĭurrent evidence shows that ondansetron but not domperidone is effective for the treatment of AGE‐associated vomiting in the emergency setting. Nearly 80% of Italian pediatricians prescribe antiemetic drugs to children with AGE, mostly off‐label. ![]() ![]() Vomiting is the presenting symptom in up to 75% of children with acute gastroenteritis (AGE), where it contributes to fluid loss, failure of oral rehydration therapy, and emergency admission to the hospital. Vomiting is a common symptom in childhood and has many causes, ranging from self‐limited to life‐threatening conditions. ![]()
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